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Research Interests
Optics in medicine, biomedical imaging to guide cancer therapy; dose imaging in radiation therapy; Cherenkov light imaging
Education
- Bc, Czech Technical University 2008
- MSc, Czech Technical University 2010
- PhD, Biomedical Physics, Czech Technical University 2014
Awards
- Best in Physics‘ Imaging Award for "3D Cherenkov Sheet Molecular Imaging provides 100 micron whole body spatial resolution," American Association of Physicists in Medicine (AAPM) Annual Meeting, 2017.
Selected Publications
- BW Pogue, J Feng, EP LaRochelle, P Brůža, H Lin, R Zhang, JR Shell, et al. Maps of in vivo oxygen pressure with submillimetre resolution and nanomolar sensitivity enabled by Cherenkov-excited luminescence scanned imaging. Nature Biomedical Engineering 2(4), 254, 2018.
- T Gorkhover, A Ulmer, K Ferguson, M Bucher, F Maia, J Bielecki, T Ekeberg, MF Hantke, BJ Daurer, C Nettelblad, J Andreasson, A Barty, P Brůža, et al. Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles. Nature Photonics 12(3), 150, 2018.
- JD Koralek, JB Kim, P Brůža, CB Curry, Z Chen, HA Bechtel, AA Cordones, P Sperling, S Toleikis, JF Kern, SP Moeller, SH Glenzer, DP DePonte. Generation and characterization of ultrathin free-flowing liquid sheets. Nature Communications 9(1), 1353, 2018.
- P Brůža, SL Gollub, JM Andreozzi, II Tendler, BB Williams, LA Jarvis et al. Time-gated scintillator imaging for real-time optical surface dosimetry in total skin electron therapy. Physics in Medicine and Biology 63(9):095009, 2018.
- JM Andreozzi, KE Mooney, P Brůža, A Curcuru, DJ Gladstone, BW Pogue, O Green. Remote Cherenkov Imaging Based Quality Assurance of a Magnetic Resonance Image Guided Radiotherapy System. Medical Physics, 2018.
- P Brůža, JM Andreozzi, DJ Gladstone, LA Jarvis, J Rottmann, BW Pogue. Online Combination of EPID & Cherenkov Imaging for 3-D Dosimetry in a Liquid Phantom. IEEE Transactions on Medical Imaging 36(10), 2099-2103, 2017.
- P Brůža, H Lin, SA Vinogradov, LA Jarvis, DJ Gladstone, BW Pogue. Light sheet luminescence imaging with Cherenkov excitation in thick scattering media. Optics Letters 41(13), 2986-2989, 2016.
- P Brůža, D Pánek, M Vrbová, V Fidler, C Rose-Petruck. Spatial frequency heterodyne imaging in the soft x-ray water window. Applied Physics Letters 104(25), 254101, 2014.
- P Brůža, V Fidler, M Nikl. Table-top instrumentation for time-resolved luminescence spectroscopy of solids excited by nanosecond pulse of soft X-ray source and/or UV laser. Journal of Instrumentation 6(09), P09007, 2011.
Courses
- ENGG 168: Biomedical Radiation Transport
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