Petr Brůža

Research Interests

Optics in medicine, biomedical imaging to guide cancer therapy; dose imaging in radiation therapy; Cherenkov light imaging

Education

Bc, Czech Technical University 2008
MSc, Czech Technical University 2010
PhD, Biomedical Physics, Czech Technical University 2014

Awards

Best in Physics‘ Imaging Award for "3D Cherenkov Sheet Molecular Imaging provides 100 micron whole body spatial resolution," American Association of Physicists in Medicine (AAPM) Annual Meeting, 2017.

Selected Publications

BW Pogue, J Feng, EP LaRochelle, P Brůža, H Lin, R Zhang, JR Shell, et al. Maps of in vivo oxygen pressure with submillimetre resolution and nanomolar sensitivity enabled by Cherenkov-excited luminescence scanned imaging. Nature Biomedical Engineering 2(4), 254, 2018.
T Gorkhover, A Ulmer, K Ferguson, M Bucher, F Maia, J Bielecki, T Ekeberg, MF Hantke, BJ Daurer, C Nettelblad, J Andreasson, A Barty, P Brůža, et al. Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles. Nature Photonics 12(3), 150, 2018.
JD Koralek, JB Kim, P Brůža, CB Curry, Z Chen, HA Bechtel, AA Cordones, P Sperling, S Toleikis, JF Kern, SP Moeller, SH Glenzer, DP DePonte. Generation and characterization of ultrathin free-flowing liquid sheets. Nature Communications 9(1), 1353, 2018.
P Brůža, SL Gollub, JM Andreozzi, II Tendler, BB Williams, LA Jarvis et al. Time-gated scintillator imaging for real-time optical surface dosimetry in total skin electron therapy. Physics in Medicine and Biology 63(9):095009, 2018.
JM Andreozzi, KE Mooney, P Brůža, A Curcuru, DJ Gladstone, BW Pogue, O Green. Remote Cherenkov Imaging Based Quality Assurance of a Magnetic Resonance Image Guided Radiotherapy System. Medical Physics, 2018.
P Brůža, JM Andreozzi, DJ Gladstone, LA Jarvis, J Rottmann, BW Pogue. Online Combination of EPID & Cherenkov Imaging for 3-D Dosimetry in a Liquid Phantom. IEEE Transactions on Medical Imaging 36(10), 2099-2103, 2017.
P Brůža, H Lin, SA Vinogradov, LA Jarvis, DJ Gladstone, BW Pogue. Light sheet luminescence imaging with Cherenkov excitation in thick scattering media. Optics Letters 41(13), 2986-2989, 2016.
P Brůža, D Pánek, M Vrbová, V Fidler, C Rose-Petruck. Spatial frequency heterodyne imaging in the soft x-ray water window. Applied Physics Letters 104(25), 254101, 2014.
P Brůža, V Fidler, M Nikl. Table-top instrumentation for time-resolved luminescence spectroscopy of solids excited by nanosecond pulse of soft X-ray source and/or UV laser. Journal of Instrumentation 6(09), P09007, 2011.

Patents

Dosimetry systems for radiation treatment using radiation-detector-triggered cameras to image cherenkov emissions or thin-sheet scintillators | 11,633,627