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Headshot Hixon sq

Katie Hixon

Assistant Professor of Engineering

Overview

Professor Hixon's research focuses on tissue engineering/regenerative medicine strategies to improve treatment and facilitate healing in patients with congenital and traumatic craniofacial anomalies, as well as those with delayed or failed musculoskeletal healing. Prior to joining the Dartmouth faculty, Hixon earned a PhD in biomedical engineering at Saint Louis University. Her research broadly included tissue engineering scaffold fabrication for the treatment of critical-size defects and craniofacial/maxillofacial congenital conditions. Following this, she completed a postdoctoral position in the Department of Orthopaedic Surgery at Washington University in St. Louis School of Medicine. Here she was awarded the NIH F32 Ruth L. Kirschstein National Research Service Award to study bone healing following fracture and develop a clinically relevant animal model to test therapeutic interventions. Hixon's work will continue to contribute cutting-edge research utilizing orthopaedic and craniofacial models to drive the development of novel tissue engineering/regenerative medicine therapies, impacting dental, oral, craniofacial, and musculoskeletal health.

Education

  • BS, Biomedical Engineering, University of Iowa 2014
  • PhD, Biomedical Engineering, Saint Louis University 2018

Research Interests

Tissue engineering; regenerative medicine; biomaterials and scaffolds; craniofacial reconstruction; orthopaedics; critical-size defects; fracture healing

Selected Publications

  • Hixon KR, Bogner, SJ*, Ronning-Arnesen, G*, Janowiak Mulligan BE, Sell SA. Investigating Manuka Honey Antibacterial Properties When Incorporated into Cryogel, Hydrogel, and Electrospun Tissue Engineering Scaffolds." Gels: Cryogelation and Cryogels (2019) 5(2): 21. Invited Contribution. PMID: 31003516. (* indicates authors contributed equally)
  • Hixon KR, Lu T, Carletta MN, McBride‐Gagyi SH, Janowiak BE, Sell SA. A preliminary in vitro evaluation of the bioactive potential of cryogel scaffolds incorporated with Manuka honey for the treatment of chronic bone infections. J Biomed Mater Res Part B (2018) 106B:1918–1933. PMID: 28960886
  • Alarcon De La Lastra A, Hixon KR, Aryan LM, Banks AN, Hall AF, Sell SA. Dissolvable 3D-Printed Molds for Patient Specific Craniofacial Bone Regeneration. J Funct Biomater (2018) 9(3): 46. PMID: 30042357
  • Haas G, Dunn A, Marcinczyk M, Talovic M, Schwartz M, Scheidt R, Patel A, Hixon KR, Elmashhady H, McBride-Gagyi SH, Sell SA, Garg K. Biomimetic Sponges for regeneration of skeletal muscle following trauma. J Biomed Mater Res A (2018) 107(1): 92-103. PMID: 30394640
  • Hixon KR, Carletta MN, Neal SM, Talovic M, Dunn AJ, Garg K, Sell SA. Mineralization and Antibacterial Potential of Bioactive Cryogel Scaffolds In Vitro. International Journal of Polymeric Materials and Polymeric Biomaterials (2018)
  • Hixon KR, Melvin A, Lin AY, Hall AF, Sell SA. Cryogel Scaffolds from Patient-Specific 3D-Printed Molds for Personalized Tissue Engineered Bone Regeneration in Pediatric Cleft-Craniofacial Defects. J Biomater Appl (2017) 32(5):598-611. PMID: 28980856
  • Hixon KR, Lu T, McBride-Gagyi SH, Janowiak BE, Sell SA. A Comparison of Tissue Engineering Scaffolds Incorporated with Manuka Honey of Varying UMF. Biomed Res Int (2017). PMID: 28326322
  • Hixon KR, Lu T, Sell SA. A Comprehensive Review of Cryogels and Their Roles in Tissue Engineering Applications. Acta Biomater (2017) 62(Supplement C): 29-41. PMID: 28851666
  • Hixon KR, Eberlin CT, Lu T, Neal SM, McBride-Gagyi SH, Sell SA. The Calcification Potential of Cryogel Scaffolds Incorporated with Various Forms of Hydroxyapatite for Bone Regeneration. Biomed Mater (2017). PMID: 28145891
  • Hixon KR, Eberlin CT, Kadakia PU, McBride-Gagyi SH, Jain E, Sell SA. A Comparison of Cryogel Scaffolds to Identify an Appropriate Structure for Promoting Bone Regeneration. Biomedical Physics & Engineering Express (2016) 2(3): 035014
  • Kadakia PU, Jain E, Hixon KR, Eberlin CT, Sell SA. Sonication induced silk fibroin cryogels for tissue engineering applications. Materials Research Express (2016) 3(5): 055401.
  • Hixon K, Rhea L, Standley J, Canady FJ, Canady JW, Dunnwald M. Interferon Regulatory Factor 6 Controls Proliferation of Keratinocytes from Children With Van der Woude Syndrome. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2016) 54(3):281-286. PMID: 2711556

Awards

  • F32 Ruth L. Kirschstein National Research Service Award (NRSA), 2019–2021
  • Rising Star in Engineering in Health (Columbia University), 2020
  • Society of Women Engineers (SWE) St. Louis Service Award, 2018
  • Graduate Dissertation Fellow (Saint Louis University), 2017–2018
  • Brennan Summer Fellow (Saint Louis University), 2017
  • Outstanding Graduate Student Award (Saint Louis University), 2016

Professional Activities

  • Education Initiatives Committee, International Section of Fracture Repair (ISFR), ORS (2019–present)
  • Member, American Society for Bone and Mineral Research (ASBMR)
  • Member, Biomedical Engineering Society (BMES)
  • Member, Orthopaedic Research Society (ORS)
  • Member, Society of Women Engineers (SWE)
  • Member, American Association for the Advancement of Science (AAAS)