Metabolic engineering combines aspects of chemical engineering, systems biology and synthetic biology. Researchers study enzyme activity, mass balance, and thermodynamics using key genetic and computational techniques, including CRISPR, COBRA and Equilibrator. Active projects at Dartmouth include enzyme therapeutics, cell-based protein purification systems, and improving the properties and performance of bacteria for production of cellulosic biofuels.

Our collective research activities can be mapped onto a landscape defined by both impact (health and energy), and scale (molecular, cellular, and systems).