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Protein engineering techniques have the potential to redesign nature's biocatalysts at the molecular level and generate novel biomolecules with superior targeted activity. Active projects at Dartmouth include novel protein expression systems, therapeutic protein deimmunization, and vaccine design.
Our collective research activities can be mapped onto a landscape defined by both impact (health and energy), and scale (molecular, cellular, and systems).
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Research Subfields
Cell-based protein purification systems
Cellular engineering of protein expression hosts
Glyco-engineering of proteins
Novel protein expression systems
Protein engineering tools in immunology
Therapeutic protein deimmunization