This course will provide a comprehensive introduction to the design, modeling, and experimental implementation of synthetic bio-molecular circuits in living cells, which have wide applications in biotechnology and medicine. Simple but sophisticated synthetic biological circuits will be implemented and tested in microbial cells in the laboratory. Computer aided design, modeling, and simulation will use an industry standard electronic circuit design tool showing how to design, model, and fit actual experimental biological data such that engineering circuit theory and biological experiment agree.
MATH 3 or MATH 8 or equivalent experience in Basic Calculus, CHEM 5, BIOL 13. Experience in Molecular Biology is useful (e.g. ENGS 35, BIOL 45, & BIOL 46 or equivalent) but not necessary. Experience in Signals and System Modeling is also useful (e.g. ENGS 22) but not necessary.