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Alexander Boys

Assistant Professor of Engineering

Professor Boys' laboratory examines new ways to interface cells with electronic systems to create two-way interfaces with the body. Image: Microelectrodes bound onto a single stem cell. 

Overview

Professor Boys is a materials scientist and biomedical engineer focusing on developing integrative bioelectronic implants for interacting with the body. Prior to joining Dartmouth, Boys earned a PhD in materials science and engineering at Cornell University, where he studied interfacial tissues to develop living implant systems through an NIH F31 fellowship. After this, he moved overseas to the University of Cambridge to work on tissue engineered bioelectronic implants for interfacing with the nervous system through an HFSP cross-disciplinary fellowship.

Research Interests

Bioelectronics; tissue engineering; implant science

Education

  • BS, Materials Science & Engineering, Lehigh University 2013
  • MS, Materials Science & Engineering, Cornell University 2016
  • PhD, Materials Science & Engineering, Cornell University 2019

Awards

  • Jesus College, University of Cambridge CPDA, 2020
  • HFSP Cross-disciplinary Fellowship, 2020
  • NIH F31 Fellowship, 2017
  • NSF EAPSI Scholarship, 2016
  • Dow Scholarship, 2013
  • Bradley Stoughton Student Award, 2013

Selected Publications

  • Oldroyd P, Velasco-Bosom S, Bidinger SL, Hasan T, Boys AJ**, Malliaras GG**. (2025) "Fabrication of thin-film electrodes and organic electrochemical transistors for neural implants." Nature Protocols. DOI: 10.1038/s41596-024-01116-6. **Co-corresponding author.
  • Carnicer Lombarte A, Boys AJ, Güemes Gonzalez A, Gurke J, Velasco Bosom S, Hilton S, Barone DG, Malliaras GG. (2024) "Ultraconformable cuff implants for long-term bidirectional interfacing of peripheral nerves at sub-nerve resolutions." Nature Communications. 15: 7523. DOI: 10.1038/s41467-024-51988-1.
  • Boys AJ*, Keene ST. (2024) "Bioelectronic interfacial matching for superior implant design." Cell Reports Physical Science. 5: 101877. DOI: 10.1016/j.xcrp.2024.101877. *Corresponding author.
  • Boys AJ*. (2024) "There and back again: Building systems that integrate, interface, and interact with the human body." Advanced Biology. 2300366. DOI: 10.1002/adbi.202300366. *Corresponding author.
  • Mack S, Barron SL, Boys AJ*. (2023) "Digesting digestion: An educational laboratory to teach students about enzymes and the gastrointestinal tract." Journal of Chemical Education. 100(2): 907–913. DOI: 10.1021/acs.jchemed.2c00992. *Corresponding author.
  • Boys AJ, Carnicer Lombarte A, Güemes Gonzalez A, van Niekerk DC, Hilton S, Barone DG, Proctor CM, Owens RM, Malliaras GG. (2022) "3D bioelectronics with a remodellable matrix for long-term tissue integration and recording." Advanced Materials. 2207847. DOI: 10.1002/adma.202207847.
  • Pitsalidis C, van Niekerk DC, Moysidou CM, Boys AJ, Withers AM, Vallet R, Owens RM. (2022) "Organic electronic transmembrane devices for hosting and monitoring 3D cell cultures." Science Advances. 8(37): eabo4761. DOI: 10.1126/sciadv.abo4761.
  • Pitsalidis C, Pappa AM, Boys AJ, Moysidou CM, van Niekerk DC, Saez J, Savva A, Iandolo D, Owens RM. (2022) "In vitro organic bioelectronics." Chemical Reviews. 122(4): 4700–4790. DOI: 10.1021/acs.chemrev.1c00539.
  • Boys AJ*, Walsh M. (2019) "Introducing engineering design and materials science at an earlier age through ceramic cold casting." Journal of Chemical Education. 96(1): 104–109. DOI: 10.1021/acs.jchemed.8b00404. *Corresponding author.
  • Boys AJ, Kunitake JAMR, Henak CR, Cohen I, Estroff LA, Bonassar LJ. (2019) "Understanding the stiff-to-compliant transition of the meniscal attachments through spatial correlation of composition, structure, and mechanics." ACS Applied Materials & Interfaces. 11: 26559–26570. DOI: 10.1021/acsami.9b03595.

Research Quick Takes

Graphic of a human cellular matrix surrounding a circular foreign body

Mar 28, 2024

Interface Design for Bioelectronic Implants

Professor Alex Boys co-authored "Bioelectronic interfacial matching for superior implant design" published in Cell Reports Physical Science, including discussion of the relevance of different mechanical and electronic factors. "Interface design is an important aspect for any material that is implanted into the body," says Boys, "and we wanted to provide a framework for researchers who work on bioelectronics to think about this important issue."