ENGS 161: Metabolic Engineering


20W: 12

21W: 12


  • ENGS 35 or ENGS 160
  • a non-introductory course in biochemistry, molecular biology, or permission

A consideration of analysis and manipulation of metabolism pursuant to applied objectives.  We will start with an overview of cellular metabolism and physiology, first from an extracellular perspective and then from an intracellular perspective, with a focus on unicellular micoorganisms.  Techniques of quantitative intracellular analysis and metabolic pathway engineering will be considered in some detail, followed by genome editing and applications to the human body. A quantitative perspective will be taken throughout, with frequent reference to examples from the primary literature.