Jay C. Buckey Jr.

Research Interests

Bubble detection and sizing; smart medical systems; hearing assessment; aerospace medicine; undersea and hyperbaric medicine; technology and energy policy; motion sickness

Education

• BSEE, Cornell University 1977
• MD, Cornell University 1981

Research Projects

• How sound processing in the ear and brain relates to educational outcomes, mental health, and quality of life in adolescents living with HIV

  How sound processing in the ear and brain relates to educational outcomes, mental health, and quality of life in adolescents living with HIV

  The focus is determining if tests of central auditory function (i.e., tests of the brain’s ability to process sound) are associated with, or predict, the development of literacy and neurocognitive abilities.

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• Testing and delivery of hyperbaric chamber for MRI

  Testing and delivery of hyperbaric chamber for MRI

  The goal of this project is to develop a hyperbaric chamber suitable for use in an MRI machine to assess the effects of hyperbaric gases such as oxygen on various functions.

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• Physiological monitoring to accelerate safe decomposition

  Physiological monitoring to accelerate safe decomposition

  This project is examining the use of a novel bubble detector, along with a suite of other physiological monitors, to increase the safety of dives.

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• Hyperbaric oxygen therapy for ulcerative colitis patients hospitalized for moderate to severe flares: a phase 3 multi-center, randomized, double-blind, sham-controlled trial

  Hyperbaric oxygen therapy for ulcerative colitis patients hospitalized for moderate to severe flares: a phase 3 multi-center, randomized, double-blind, sham-controlled trial

  The goal of this project is to investigate in a multicenter, randomized trial whether hyperbaric oxygen can improve outcomes for patients with moderate to severe ulcerative colitis who are admitted for treatment of a flare of their disease.

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• ExMC: Ultra-compact urinary calcium measurement device HHC inscop and sensory augmentation

  ExMC: Ultra-compact urinary calcium measurement device HHC inscop and sensory augmentation

  This is an augmentation request to evaluate intranasal scopolamine (INSCOP) for motion sickness prevention and treatment.

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• Ultra-compact urinary calcium measurement device: refinement and application

  Ultra-compact urinary calcium measurement device: refinement and application

  To develop small, low power, operationally acceptable technology that could be used to monitor the risk of kidney stone formation and rate of bone loss. This would allow for targeted countermeasures to those who need them the most.

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• Advancing and applying peripheral and central auditory findings in HIV/AIDS

  Advancing and applying peripheral and central auditory findings in HIV/AIDS

  To determine whether worsening of central auditory test performance precedes the development of cognitive deficits in PLWH.

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• Altered auditory networks in HIV-induced central nervous system dysfunction

  Altered auditory networks in HIV-induced central nervous system dysfunction

  To evaluate central nervous system auditory networks using MR imaging and determine how changes in these networks are affected by HIV infection and treatment.

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• Quantification of response to virtual reality-based sensory stimulation for relaxation and therapeutic release in ICE

  Quantification of response to virtual reality-based sensory stimulation for relaxation and therapeutic release in ICE

  The major goal of this project is to develop a virtual reality system including haptic
  cues that can be used to provide relaxation and attention restoration in isolated and confined
  environments. We are collaborating with the Australian Antarctic Project (under the
  Australian Government’s Department of Agriculture, Water, and the Environment with head
  offices located in Kingston, Tasmania) on this award; we are using data collected.

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Selected Publications

• Moses RA, Hunter AE, Brandes ER, Zhang Z, Rees JR, Peacock JL, Bihrle W 3rd, Sethuraman K, Weaver LK, Buckey JC Jr. (2024) "Patient-Reported Outcome Measures Following Hyperbaric Oxygen Therapy for Radiation Cystitis: Early Results From the Multicenter Registry for Hyperbaric Oxygen Therapy." Journal of Urology. 211(6): 765-774. https://doi.org/10.1097/JU.0000000000003929.
• Ealer C, Niemczak CE, Nicol T, Magohe A, Bonacina S, Zhang Z, Rieke C, Leigh S, Kobrina A, Lichtenstein J, Massawe ER, Kraus N, Buckey JC. (2024) "Auditory Neural Processing in Children Living with HIV Uncovers Underlying Central Nervous System Dysfunction." AIDS. 38(3): 289-298. https://doi.org/10.1097/QAD.0000000000003771.
• Buckey JC, Lan M, Phillips SD, Archambault-Leger V, Fellows AM. (2022) "A Theory for Why the Spaceflight-Associated Neuro-Ocular Syndrome Develops." Journal of Applied Physiology (1985). 132(5): 1201-1203. https://doi.org/10.1152/japplphysiol.00854.2021.
• Lan M, Phillips SD, Archambault-Leger V, Chepko AB, Lu R, Anderson AP, Masterova KS, Fellows AM, Halter RJ, Buckey JC. (2021) "Proposed Mechanism for Reduced Jugular Vein Flow in Microgravity." Physiological Reports. 9(8): e14782. https://doi.org/10.14814/phy2.14782.
• Stankovic AS, Alvarenga DL, Coleman Daniels VR, Simmons RG, Buckey JC, Putcha L. (2019) "Intranasal Scopolamine for Motion Sickness." Aerospace Medicine and Human Performance. 90(11): 917-924. https://doi.org/10.3357/AMHP.5456.2019.
• Buckey JC, Fellows AM, Magohe A, Maro I, Gui J, Clavier O, Massawe E, Moshi N. (2019) "Hearing Complaints in HIV Infection Originate in the Brain Not the Ear." AIDS. 33(9): 1449-1454. https://doi.org/10.1097/QAD.0000000000002229.
• Dulai PS, Buckey JC Jr, Raffals LE, Swoger JM, Claus PL, O’Toole K, Ptak JA, Gleeson MW, Widjaja CE, Chang JT, Adler JM, Patel N, Skinner LA, Haren SP, Goldby-Reffner K, Thompson KD, Siegel CA. (2018) "Hyperbaric Oxygen Therapy Is Well Tolerated and Effective for Ulcerative Colitis Patients Hospitalized for Moderate-Severe Flares: A Phase 2A Pilot Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial." American Journal of Gastroenterology. 113(10): 1516-1523. https://doi.org/10.1038/s41395-018-0005-z.
• Anderson AP, Mayer MD, Fellows AM, Cowan DR, Hegel MT, Buckey JC. (2017) "Relaxation with Immersive Natural Scenes Presented Using Virtual Reality." Aerospace Medicine and Human Performance. 88(6): 520-526. https://doi.org/10.3357/AMHP.4747.2017.
• Sandoval LR, Buckey JC, Ainslie R, Tombari M, Stone W, Hegel MT. (2017) "Randomized Controlled Trial of a Computerized Interactive Media-Based Problem-Solving Treatment for Depression." Behavior Therapy. 48(3): 413-425. https://doi.org/10.1016/j.beth.2016.04.001.
• Swan JG, Wilbur JC, Moodie KL, Kane SA, Knaus DA, Phillips SD, Beach TL, Fellows AM, Magari PJ, Buckey JC. (2014) "Microbubbles Are Detected Prior to Larger Bubbles Following Decompression." Journal of Applied Physiology (1985). 116(7): 790-796. https://doi.org/10.1152/japplphysiol.01156.2013.
• Buckey JC Jr, Gaffney FA, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Yancy CW Jr, Meyer DM, Blomqvist CG. (1996) "Central Venous Pressure in Space." Journal of Applied Physiology (1985). 81(1): 19-25. https://doi.org/10.1152/jappl.1996.81.1.19.
• Buckey JC Jr, Lane LD, Levine BD, Watenpaugh DE, Wright SJ, Moore WE, Gaffney FA, Blomqvist CG. (1996) "Orthostatic Intolerance After Spaceflight." Journal of Applied Physiology (1985). 81(1): 7-18. https://doi.org/10.1152/jappl.1996.81.1.7.

Books

Space Physiology

Oxford University Press, 2006

The Neurolab Spacelab Mission: Neuroscience Research in Space

National Aeronautics and Space Administration, Lyndon B. Johnson Space Center, 2003

News

Polaris Dawn Project Aims to Prevent Bone Loss in Space
Sep 10, 2024

Former Astronaut Jay Buckey Talks About Dealing With Isolation
Apr 07, 2020

Dartmouth's Astronaut-Physician Remembers John Glenn
Dec 14, 2016

To Sustain Astronauts' Mental Health, Dartmouth-Led Team Testing New Virtual Reality Tech in Arctic
Jan 06, 2016

Liliana Ma '14: On Research and Thinking Outside the Box
May 27, 2014

Astronaut and Professor Jay Buckey on the Future of NASA and its Human Spaceflight Program
Jul 29, 2011

In the News