2024 Investiture Information

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Special Seminar: Multimodal Microscopic and Endoscopic Biomedical Imaging Technologies



3:30pm - 4:30pm ET


Meeting ID: 951 4202 1459
Passcode: 113629

The combined use of different imaging modalities can provide a comprehensive evaluation by compensating for limitations of each individual technique. However, increased procedure length, associated risks, and additional efforts on imaging co-registration cannot be overlooked. Therefore, a technique that can simultaneously perform multiple imaging modalities would greatly improve clinical outcomes.

My research focuses on the development of novel microscopic and endoscopic multimodal optical imaging technologies, which enables simultaneous imaging of different modalities through one catheter and system. To solve different clinical problems, I have developed several different kinds of multimodal imaging technologies, including intravascular tri-modality optical coherence tomography/ultrasound/fluorescence, ultrafast endoscopic photoacoustic and ultrasound, ultrahigh sensitive optical coherence elastography, and 1.7-micron optical coherence elastography angiography. Additionally, several technical innovations were proposed and implemented for further optimization. In addition to imaging technologies, I have developed a new anti-vascular technique, OCT guided photo mediated ultrasound therapy. This therapy applies laser pulse and ultrasound burse simultaneously to promote cavitation activity, and therefore is capable of destructing the blood vessel with improved safety and efficacy.

Overall, my research is multidisciplinary, involving optical engineering, system integration, imaging processing, and data acquisition. In this talk, I will

  1. introduce how to design and construct a multimodal optical imaging system and catheter, and
  2. discuss scientific innovations and technical challenges of my studies in the field of cardiology, gastroenterology, ophthalmology, and dermatology.

Additionally, prospective strategies of ongoing studies and future plans will be discussed.

About the Speaker(s)

Yan Li
Senior Engineer, Boston Scientific

Yan Li

Yan Li received her PhD in biomedical engineering at the University of California, Irvine in 2020, and worked there as a postdoctoral research fellow. Currently, she is a senior engineer at Boston Scientific. Her research interests include optical coherence elastography, optical coherence tomography, photoacoustic imaging, and multimodal endoscopy. She has first-authored more than 20 peer-reviewed publications in leading journals of biomedical engineering (including Light: Science & Applications and IEEE Transactions on Medical Imaging), as well as two book chapters. She is the recipient of an American Heart Association predoctoral fellowship, an American Heart Association postdoctoral fellowship, an ASLMS student grant, a SESASC fellowship, and a UCI public impact fellowship.


For more information, contact Ashley Parker at ashley.l.parker@dartmouth.edu.