Micro- and Nano-Fabrication for Encapsulated Cell Therapy

Barjor Gimi, Dartmouth College

Friday, April 11, 2014, 3:30pm

Spanos Auditorium

This seminar is part of the Jones Seminars on Science, Technology, and Society series.

A nanoporous capsule that protects insulin-secreting cells from the immune system vastly expands the source of therapeutic cells available for grafting in people with diabetes, including cells from animal sources, stem cells, and genetically engineered cells. These encapsulated cellular grafts potentially provide an endogenous, renewable, and long-term source of insulin without the need for injurious pharmacological immunosuppression. This talk highlights how novel micro- and nano-fabrication methods may be used to develop effective strategies for cell encapsulation.

About the Speaker

Barjor Gimi received his undergraduate degrees in Physics and Mechanical Engineering from Lawrence University and Washington University in St. Louis. Subsequently, he worked in the biomedical industry as a senior design engineer. He then received a doctorate degree in Bioengineering from University of Illinois and a postdoctoral degree in Radiology from Johns Hopkins. He is currently Associate Professor of Radiology and of Medicine at Dartmouth, and Director of the Biomedical NMR Research Center. His research focuses on novel technologies to encapsulate therapeutic cells to protect them from immune attack, and on imaging methods to noninvasively monitor cell function.