Special Seminar: Measuring the Dynamic Biophysical Behavior of Cells and Tissues In Vitro

Elise Corbin, Postdoctoral Research Fellow, University of Pennsylvania

Monday, April 16, 2018, 3:30–4:30pm

Rm. 100 (Spanos Auditorium), Cummings Hall

Over recent years significant progress has been made towards understanding the molecular and cellular mechanism by which cells "feel" their environment. There exists a complex relationship between the behavior of a cell, its physical properties, and its surrounding environment. Materials and devices with the ability to characterize cells and tissues in time and in response to changing stimuli have the potential to reshape our understanding of how cells interact with their micro-environments as well as the coordination of biophysical cues and regulators. My research is focused on developing microdevices, sensors, and materials for studying this dynamic, time-varying behavior, with a focus on cardiovascular and cancer applications. In this talk I will discuss my work in (1) cellular growth mechanics using mass change as a biomarker and (2) dynamic microenvironments in both 2D and 3D devices characterizing pharmacological responses and biomechanical phenotyping.

About the Speaker

Elise A. Corbin, PhD, is a Postdoctoral Research Fellow in the Perelman School of Medicine Cardiovascular Institute at the University of Pennsylvania. She received her PhD in Mechanical Engineering as an NSF Cellular and Molecular Mechanics and BioNanotechnology IGERT Fellow in 2013 from the University of Illinois at Urbana-Champaign where she worked to develop BioMEMS for single cell biomechanics. Her research is to study emergent time-dependent cellular responses with engineered microdevices.

For more information, contact Stephanie Turner at stephanie.m.turner@dartmouth.edu.