Jones Seminar: Exposure Science at US EPA—Linking environmental measurements to in vivo and in vitro biomonitoring data

Joachim Pleil, US Environmental Protection Agency

Friday, October 9, 2015, 3:30–4:30pm

Spanos Auditorium, Cummings Hall

Recent developments in environmental research have focused on the cumulative effects of the total environment on human metabolism and health state. The fundamental discipline, exposure science, is now being established as an academic specialty distinct from toxicology, epidemiology, and biology.  Exposure science has been defined as studying "human contact with chemical, physical, or biological agents occurring in their environments, [to] advance knowledge of the mechanisms and dynamics of events either causing or preventing adverse health outcomes" and is considered the "bedrock for protection of public health."  In short, exposure science encompasses the study of the external environment’s contributions to the human system as well as the chemicals already present within human biological media; these are collectively referred to as the human exposome.

About the Speaker

Joachim holds BS degrees in mathematics and physics, an MS in physics, and PhD in environmental science and engineering. He initially worked for Northrop Corp. as a Senior Scientist designing laser-based optical instrumentation and joined US EPA in 1987 as a Research Scientist developing analytical methods for measuring organic environmental pollutants. For the past 10 years he has been a subject matter expert for the US Government in human biomarker research. He has published over 100 journal articles including 40 involving breath biomarker research and the statistical interpretation of data. He serves as an adjunct professor at the University of North Carolina School of Public Health where he teaches Environmental Exposure Assessment and mentors MS and PhD students. He is a founding member of the International Association of Breath Research (IABR) and the Submarine Air Monitoring and Purification (SAMAP) organization, serves on the editorial board of Biomarkers and is the editor-in-chief of the Institute of Physics' Journal of Breath Research.

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