Jones Seminar: Comprehensive Multi-Dimensional Gas Chromatography for Targeted and Non-Targeted Analyses—Advances and Perspectives

John Dimandja, Science Advisor, Food and Drug Administration

Friday, October 2, 2015, 3:30–4:30pm

Spanos Auditorium, Cummings Hall

The field of comprehensive multidimensional gas chromatography (GCxGC) has progressed significantly in the past decade through a variety of applications by a growing number of practitioners in industry, academia, and governmental agencies. Although initially developed as a high-resolution technique for the separation of mixtures of volatile organics, the ability to produce structured chromatograms is widening the scope of GCxGC investigations for both targeted and non-targeted analyses of complex samples, particularly when combined with mass spectrometric detection.

In this talk an overview of the figures-of-merit of the technology will be given, and recent advances in GCxGC method development strategies will be discussed using examples of projects developed by leading laboratories around the world.  Finally, and outline of key factors needed for the establishment of GCxGC technology in routine method validation protocols will be provided.

About the Speaker

Dr. Jean-Marie (John) Dimandja received his PhD in Analytical Chemistry from Southern Illinois University, where he was a student in the late Prof. John B. Phillips’s research group at the time of the invention of comprehensive two-dimensional gas chromatography (GCxGC). Dr. Dimandja was a research scientist in the Solar System Exploration Branch at the NASA/Ames Research Center (in Mountain View, California) from 1991 to 1997, then moved to Atlanta, Georgia, where he was a research scientist in the Toxicology Branch at CDC’s National Center for Environmental Health from 1997 to 2002. In 2002 he transitioned to academia, where he worked as a tenured Chemistry professor at Spelman College and as a research professor at Georgia Tech’s Institute of Bioengineering and Biosciences. He maintained a research group funded by federal grants from NSF, NIH, NASA, and NIST, as well as corporate support from several companies (Kimberly Clark, IFF, LECO, Lockheed, etc.). Dr. Dimandja has authored nearly 40 peer-reviewed publications and 250 conference presentations, and has organized and/or chaired several conference symposia on GCxGC at PITTCON, ACS, and ISCC.  He has served as a science advisor at the Food and Drug Administration (FDA) since 2007, and has recently become the Branch Director of their Southeast Regional Tobacco Laboratory.

For more information, contact Haley Tucker at