Models of cerebral circulation, gas exchange and regulatory physiology

Models of cerebral circulation, gas exchange and regulatory physiology are increasingly important tools for the interpretation of neuroimaging data. For instance, biophysical models can describe dynamic cerebral autoregulation (CA), which maintains relatively constant cerebral blood flow despite changes in arterial blood pressure. Medical images that spatially map CA function could provide important new information to improve treatment decisions for patients with traumatic brain injury (TBI). Better models of the background physiological fluctuations in neuroimaging data can also help to isolate the functional hemodynamic response to brain activity.

Faculty contact: Solomon G. Diamond