Mechanics of morphogenesis in embryonic development

The morphogenesis (generation of biological form) in embryos brings forthmore challenges in mechanics that are closely related to preventing and treating cognitive diseases. During development, the tissues bend, fold, and/or twist and mechanical cues are believed to be conveying important information necessary for normal development. Understanding the role of mechanical stresses and strains is key to deciphering morphogenesis indevelopment. Our group works on the mechanics of morphogenesis in brain and heart development to address the fundamental physical mechanisms at play in both normal development and in the case of congenital neurological and heart defects, the understanding of which will potentially lead to the treatment or prevention of such defects. This research will feature a combination of biological experiments and numerical simualtions.

Faculty contact: Zi Chen