Frederic Leblond
Adjunct Assistant Professor of Engineering
frederic.leblond@dartmouth.edu
Education
- B.Eng., École Polytechnique de Montréal (1996)
- M.Sc., Physics, Université Laval (1998)
- Ph.D., Physics, McGill University (2003)
Research Interests
Biomedical optics technology for cancer imaging; small animal fluorescence imaging; fluorescence-guided surgery; diffuse optical tomography; multi-modality medical imaging; models for light propagation in tissue; inverse problem resolution methods
Current Research Projects
Selected Publications
- F. Leblond, K.M. Tichauer, R.W. Holt, F. El-Ghussein, B.W. Pogue, "Toward whole-body optical imaging of rats using single-photon counting fluorescence tomography," Optics Letters, 36 (19), 3723-5 (2011).
- F. Leblond, Z. Ovanesyan, S.C. Davis, P.A. Valdes, A. Kim, B.C. Wilson, A. Hartov, B.W. Pogue, K.D. Paulsen, D.W. Roberts, "Analytic expression of fluorescence-ratio detection provides an estimate of depth in multi-spectral sub-surface imaging," Physics in Medicine and Biology, 56 (21), 6823-6837 (2011).
- P.A. Valdes, F. Leblond, A. Kim, K.D. Paulsen, B.T. Harris, B.C. Wilson, X. Fan, T. Tosteson, A. Hartov, S. Ji, D.W. Roberts, "Quantitative fluorescence in intracranial tumors: implications for ALA-induced PpIX as an intraoperative biomarker," Journal of Neurosurgery, 115 (1), 11-7 (2011).
- F. Leblond, S.C. Davis, P.A. Valdes, B.W. Pogue, "Preclinical whole-body fluorescence imaging: Review of instruments, methods and applications," Journal of Photochemistry and Photobiology B: Biology, 98 (1), 77-94 (2010).
Awards
- NIH - NCI K-25 Career Development Award (2009 - )
- Natural Sciences and Engineering Research Council of Canada (NSERC) Post Doctoral Fellowship (2003-2005)
- Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Fellowship (1999-2001)
- Clay Mathematics Institute Scholarship (2001)
- Research Fund for Nature and Technology Postgraduate Fellowship (1998-1999)
Selected Patents
- F. Leblond, D.W. Roberts, B.W. Pogue, K.D. Paulsen, A. Hartov, S. C. Davis, D. Kepshire, "Method and apparatus for depth-resolved fluorescence, chromophores, and oximetry imaging for lesion identification during surgery," U.S. Patent application, filed in 2009
- F. Leblond, S. Fortier, "Diffuse optical fluorescence tomography using time resolved data acquired in transmission," filed January 2007, U.S. Provisional Patent application
- N. Mincu, F. Leblond, O. Guilman, X. Intes, M. Khayat, "Method and apparatus for optical image reconstruction using contour determination," filed December 2006, U.S. Provisional Patent application
Professional Activities
- Reviewer: Journal of Biomedical Optics, Journal of Optical Society of America A, Optics Letters, Medical Physics, Physics in Medicine and Biology, Inverse Problems, Biophysical Journal, IEEE Transactions in Medical Imaging
- Member, Optical Society of America (OSA)
- Member, SPIE
- Member, The Society for Molecular Imaging (SMI)
- Member, International Society for Inverse Problems in Science and Engineering (ISIPSE)
News
Quantifying intraoperative fluorescence
Medical Physics Web
January 18, 2013Research at Dartmouth-Hitchcock helps battle brain tumors
WCAX-TV
December 27, 2012Fluorescence-Guided Tumor Resection And MRI Enhancement Show Potential
Medical News Today
May 6, 2009
In Dartmouth Engineer Magazine
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Faculty News: New Profs Arrive
Winter 2009











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